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The scientists in Cologne were, in fact, able to confirm this in the laboratory. They organise themselves in small clusters which are transported by actin in the direction of the centre of the synapse. A hierarchical, data-driven approach to modeling single-cell populations predicts latent causes of cell-to-cell variability. These are nerve cells that perceive painful stimuli. Helmholtz - Gemeinschaft Deutscher Forschungszentren. T-cells red and B-cells blue form immunological synapses at their contact point green. Print Send per email Share. We only use this information for improving our services.

  • Press Release – Helmholtz Zentrum München
  • News and Events — Bernstein Netzwerk Computational Neuroscience
  • Media Coverage current — Bernstein Netzwerk Computational Neuroscience
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  • Press Release – Helmholtz Zentrum München

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    News and Events — Bernstein Netzwerk Computational Neuroscience

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    Cell Reports,DOI: The authors hope that in the future, these results will contribute to a better understanding of the role that tissue changes play in a wide range of painful diseases.

    The antigen receptors are small and are repelled by the large adhesion molecules. From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity. There you may also change your settings later.

    Media Coverage current — Bernstein Netzwerk Computational Neuroscience

    By using our website, you agree to the use of cookies. A hierarchical, data-driven approach to modeling single-cell populations predicts latent causes of cell-to-cell variability.

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    The large adhesion molecules accumulate around them in an outer ring.

    The authors hope that in the future, these results will contribute to a better understanding of the role that tissue changes play in a wide range of painful diseases. Necessary cookies Only cookies permitted that are required for the basic functionality of our websites. The scientists in Cologne were, in fact, able to confirm this in the laboratory.

    If a stronger reaction to NGF is observed in the cells, this could be caused by an increased number of NGF-responsive cells which are adhering to the matrix.

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    Researchers of the Helmholtz Centre for Infection Research HZI and the Braunschweig Integrated Centre of Systems Biology BRICSin collaboration with researchers at the University of Oxford UKhave now simulated the dynamic arrangement of these components using computer models and have subsequently been able to make inferences on the mechanisms involved in the formation of synapses.

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    We only use this information for improving our services. This, however, could not be proved for the other molecules. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle. To achieve this, however, immune cells must be able to recognise intruders and to classify them as dangerous or harmless.

    Tim Hucho from the University Hospital Cologne examined so-called nociceptive neurons.

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    Involved Groups Systems Immunology. Microscope image shows an immunological synapse. The authors hope that in the future, these results will contribute to a better understanding of the role that tissue changes play in a wide range of painful diseases.

    Different immune cells are therefore constantly in search of foreign molecules indicating the presence of any pathogen which needs to be destroyed. In order to test the method, a team of researchers headed by Prof.

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